Cochlear Damage Affects Neurotransmitter Chemistry in the Central Auditory System

Cochlear Damage Affects Neurotransmitter Chemistry in the Central Auditory System

Tinnitus, the perception of a monotonous sound not actually present in the environment, affects nearly 20% of the population of the United States. Although there has been great progress in tinnitus research over the past 25 years, the neurochemical basis of tinnitus is still poorly understood. We review current research about the effects of various types of cochlear damage on the neurotransmitt...

Neurotransmitter transporters in the central nervous system.

The Cochlear Implant in Action: Molecular Changes Induced in the Rat Central Auditory System

Dynamic fidelity control to the central auditory system: synergistic glycine/GABAergic inhibition in the cochlear nucleus.

GABA and glycine are the major inhibitory transmitters that attune neuronal activity in the CNS of mammals. The respective transmitters are mostly spatially separated, that is, synaptic inhibition in the forebrain areas is mediated by GABA, whereas glycine is predominantly used in the brainstem. Accordingly, inhibition in auditory brainstem circuits is largely mediated by glycine, but there are...

Auditory Lateralization Ability in Children with (Central) Auditory Processing Disorder

Objectives: The aim of the present study was to assess the auditory lateralization ability in children with (central) auditory processing disorder. Methods: Participants were divided in two groups: 15 children with Central Auditory Processing Disorder (8-10 years) and 80 normal children (8-11 years) from both genders with pure-tone air-conduction thresholds better than 20 dB HL bilaterally a...